👉 ClR (Chloroquine Resistance Mechanism) research focuses on understanding and developing strategies to counteract the genetic mutations that lead bacteria to become resistant to chloroquine, a widely used antimalarial and tuberculosis drug. These resistance mechanisms can involve changes in the bacterial cell's membrane, altering drug uptake, or enhancing drug efflux. Researchers study these mechanisms to identify new targets for drug development and to design more effective treatment strategies, such as combination therapies that can overcome resistance. Understanding ClR is crucial for maintaining the efficacy of chloroquine and other antimalarial drugs in the face of evolving bacterial resistance.
